A clinical-grade alternative to Promethease & Genetic Genie
If your Promethease report expired, or Genetic Genie gave you a single methylation panel, GeneLab reads the same raw DNA file into a full, interpreted health report, with pharmacogenomics, disease-risk, and an AI assistant that answers your questions. Delivered in 8 to 12 hours.
Upload the same 23andMe or AncestryDNA raw file
Useful tools, with real limits
Promethease
A low-cost report that pulls SNPedia literature into a long, searchable list of annotations. It was acquired by MyHeritage in 2019, reports expire, and it has seen little development since. The output is raw research, not an interpreted report, and there is no support line.
Genetic Genie
A free tool focused on a methylation and detox panel (MTHFR, COMT and related genes) from 23andMe raw data. It is handy and free, but narrow, tied to older file versions, and centred on variants whose clinical value is still debated.
GeneLab
A clinical-grade report across traits, carrier status, pharmacogenomics, and hereditary risk, sourced against ClinVar and PharmGKB, with an AI assistant that reads your genome alongside your blood work. One-time price, actively supported.
Promethease vs Genetic Genie vs GeneLab
The same raw DNA file, three very different reports.
| Promethease | Genetic Genie | GeneLab | |
|---|---|---|---|
| What you get | Raw SNPedia annotation list | Methylation / detox panel | Interpreted clinical-grade report |
| Scope | Broad but unstructured | Narrow (MTHFR, COMT) | Traits, carrier, PGx, disease risk |
| Pharmacogenomics | Scattered in the list | No | Yes, as a panel |
| AI assistant + blood work | No | No | Yes (Max Plan) |
| Support | Minimal | None | Yes |
| Report stays yours | Expires | Free, on-screen | Encrypted PDF + JSON/CSV |
| Price | Low, one-time | Free | From $79, one-time |
Promethease and Genetic Genie are independent tools and are not affiliated with GeneLab. This comparison reflects their publicly described features at the time of writing.
Bring the same raw file
Whatever you uploaded to Promethease or Genetic Genie works here. Upload the raw export and GeneLab builds the full report. No new swab, no second sample.
Want the detail on drug response? See the pharmacogenomic report ›
Switching from Promethease or Genetic Genie
Is Promethease still available?
Promethease still runs, but it was absorbed by MyHeritage in 2019, its reports expire, and users report broken features and little support. If your report lapsed, GeneLab reads the same raw file into a fresh, interpreted report you keep.
Is GeneLab free like Genetic Genie?
No. Genetic Genie is a free, single-panel tool. GeneLab is a paid, one-time clinical-grade analysis across many categories, with an AI assistant and real support. If you only want a methylation panel, Genetic Genie may be enough. For an interpreted whole-report read, GeneLab is built for that.
Can I upload the same raw data?
Yes. The raw export from 23andMe, AncestryDNA, or MyHeritage that you fed Promethease or Genetic Genie uploads to GeneLab directly. You can also bring a clinical VCF.
What do I get that those tools do not?
A structured, clinical-grade report sourced against ClinVar and PharmGKB, a pharmacogenomic panel, hereditary and cardiovascular risk, and an AI assistant that reads your genome alongside blood work you upload, each answer cited to the exact variant.
Give your raw DNA a report worth keeping.
Upload the same file and get a clinical-grade read before the window closes.